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Ethylene glycol is a clear, colorless, odorless, viscous liquid with a sweet taste, that can produce dramatic toxicity. It is commonly found in homes and industry. It is found most commonly in antifreeze, automotive cooling systems, and hydraulic brake fluids. In an industrial setting it is used as a solvent or as the raw material for a variety of processes. Many cases of ethylene glycol poisoning results from accidental ingestion by children who can take in large amounts since the substance tastes good. Alcoholics may also ingest this substance as an ethanol substitute.

Ethylene glycol is rapidly absorbed once it is ingested and is then widely distributed into body tissues. Peak blood levels are generally seen in one to four hours. Exposure to the skin and lungs may cause irritation but does not cause the systemic toxicity in the way that methanol does. Lethal quantities in adults are considered to be 100 ml, but in children much less may cause serious cardiac, renal, and CNS toxicity.
Ethylene glycol itself is relatively nontoxic. After absorption the unchanged compound undergoes glomerular filtration and passive reabsorption. It is then broken down into metabolites that are highly toxic and cause the associated findings of ethylene glycol toxicity. Ethylene glycol is converted to glycoaldehyde by alcohol dehydrogenase. This is the rate limiting step of a reaction in the liver that continues to breakdown the glycoaldehyde into glycolate, glyoxylate, and oxylate…
These metabolites inhibit oxidative phosphorylation, sulfhydrl-containing enzymes, and protein synthesis. Glycolic acid is the major cause of the metabolic acidosis that is seen in ethylene glycol toxicity, although glyoxylic acid also may contribute. Toxicity from ethylene glycol is produced from the above metabolites and the fact that they cause a severe acidosis, as well as from the fact that oxalate precipitates with calcium to produce widespread tissue injury in the kidney, brain, liver, blood vessels, and pericardium. Hypocalcemia may also result.

Renal Toxicity - This phase occurs 24-72 hours after ingestion and consists of flank and abdominal pain with evidence of acute tubular necrosis that is manifest as oliguric renal failure.

In article TWright603.

OLD (roshi) FUCK (bobo)

"Uncle Fester's Silent Death"

"Final Exit"

Kmene Vleshmint - "fra mauro doesn't hurts"

The keys to wrist slashing are a few things. First, you have to make long and deep cuts; not "across" your wrists, but up your arm—opens more of the vein and makes clotting harder. Second, It's best to sit and soak in a hot tub of water, or a running shower. The heat and hot water will keep your blood flowing and will relax you, but will also race your heart, as your body's natural reaction is to pump blood faster, to speed your body functions up, to cool your body off. Lastly, a little alcohol in your system can't hurt as it also prevents clotting of the blood, may stop any anxiety attacks you may have, and may even limit the pain. Lastly, elevate your legs while sitting in the tub or shower—this will bring the blood from your lower regions back into your body's center, where it can get pumped faster, and you may not get as light-headed after your bleeding.
Results of a successful wrist-slashing are this: you can expect to get cold and feel chilled all over; you will feel groggy soon after losing a lot of blood; and you will feel tired. You may feel light-headed, and will get sleepy. You will feel your heartbeat throughout your body, and a cold, eerie feeling of "pulsation" in your arms and legs, as the hours pass and your bloodpressure drops off. Average time to die on a wrist-slitting depends on your height, weight, and how large and deep the wounds are. Remember: slice up your arm to cut open that vein. Average time is at least two to four hours. Maybe longer, if you weigh more and have more body mass. Put in a CD, light a candle, drink some booze and take some sleep meds. Sit in a hot tub or shower and let it all wash away. Hope that answers your questions.